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Protein-nucleic acid interactions of LINE-1 ORF1p

Long interspersed nuclear element 1 (LINE-1 or L1) is the dominant retrotransposon in mammalian genomes. L1 encodes two proteins ORF1p and ORF2p that are required for retrotransposition. ORF2p functions as the replicase. ORF1p is a coiled coil-mediated trimeric, high affinity RNA binding protein tha...

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Detalles Bibliográficos
Autores principales: Naufer, M. Nabuan, Furano, Anthony V., Williams, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428221/
https://www.ncbi.nlm.nih.gov/pubmed/29596909
http://dx.doi.org/10.1016/j.semcdb.2018.03.019