Regulation of Intronic Polyadenylation by PCF11 Impacts mRNA Expression of Long Genes

Regulation of cleavage and polyadenylation (CPA) affects gene expression and polyadenylation site (PAS) choice. Here, we report that the CPA and termination factor PCF11 modulates gene expression on the basis of gene size. Although downregulation of PCF11 leads to inhibition of short gene expression...

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Detalles Bibliográficos
Autores principales: Wang, Ruijia, Zheng, Dinghai, Wei, Lu, Ding, Qingbao, Tian, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428223/
https://www.ncbi.nlm.nih.gov/pubmed/30840896
http://dx.doi.org/10.1016/j.celrep.2019.02.049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428223/
https://www.ncbi.nlm.nih.gov/pubmed/30840896
http://dx.doi.org/10.1016/j.celrep.2019.02.049

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