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Regulation of Intronic Polyadenylation by PCF11 Impacts mRNA Expression of Long Genes
Regulation of cleavage and polyadenylation (CPA) affects gene expression and polyadenylation site (PAS) choice. Here, we report that the CPA and termination factor PCF11 modulates gene expression on the basis of gene size. Although downregulation of PCF11 leads to inhibition of short gene expression...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428223/ https://www.ncbi.nlm.nih.gov/pubmed/30840896 http://dx.doi.org/10.1016/j.celrep.2019.02.049 |