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Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse

Routine general anesthesia is considered to be safe in healthy individuals. However, pre-clinical studies in mice, rats, and monkeys have repeatedly demonstrated that exposure to anesthetic agents during early post-natal periods can lead to acute neurotoxicity. More concerning, later-life defects in...

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Detalles Bibliográficos
Autores principales: Johnson, Simon C., Pan, Amanda, Sun, Grace X., Freed, Arielle, Stokes, Julia C., Bornstein, Rebecca, Witkowski, Michael, Li, Li, Ford, Jeremy M., Howard, Christopher R. A., Sedensky, Margaret M., Morgan, Philip G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428290/
https://www.ncbi.nlm.nih.gov/pubmed/30897103
http://dx.doi.org/10.1371/journal.pone.0213543