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miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

The interdependence of selective cues during development of regulatory T cells (Treg cells) in the thymus and their suppressive function remains incompletely understood. Here, we analyzed this interdependence by taking advantage of highly dynamic changes in expression of microRNA 181 family members...

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Detalles Bibliográficos
Autores principales: Łyszkiewicz, Marcin, Winter, Samantha J., Witzlau, Katrin, Föhse, Lisa, Brownlie, Rebecca, Puchałka, Jacek, Verheyden, Nikita A., Kunze-Schumacher, Heike, Imelmann, Esther, Blume, Jonas, Raha, Solaiman, Sekiya, Takashi, Yoshimura, Akihiko, Frueh, Jochen T., Ullrich, Evelyn, Huehn, Jochen, Weiss, Siegfried, Gutierrez, Maximiliano G., Prinz, Immo, Zamoyska, Rose, Ziętara, Natalia, Krueger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428341/
https://www.ncbi.nlm.nih.gov/pubmed/30856173
http://dx.doi.org/10.1371/journal.pbio.2006716