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Modeling differentiation-state transitions linked to therapeutic escape in triple-negative breast cancer
Drug resistance in breast cancer cell populations has been shown to arise through phenotypic transition of cancer cells to a drug-tolerant state, for example through epithelial-to-mesenchymal transition or transition to a cancer stem cell state. However, many breast tumors are a heterogeneous mixtur...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428348/ https://www.ncbi.nlm.nih.gov/pubmed/30856168 http://dx.doi.org/10.1371/journal.pcbi.1006840 |