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Development and Validation of an Immunoassay for Tenofovir in Urine as a Real-Time Metric of Antiretroviral Adherence

BACKGROUND: Pharmacologic adherence measures were critical to the interpretation of the tenofovir (TFV)-disoproxil-fumarate/emtricitabine (TDF/FTC) PrEP trials. These measures are being incorporated into PrEP demonstration projects, but currently-available metrics in plasma, cells, hair or urine inv...

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Detalles Bibliográficos
Autores principales: Gandhi, Monica, Bacchetti, Peter, Rodrigues, Warren C., Spinelli, Matthew, Koss, Catherine A., Drain, Paul K., Baeten, Jared M., Mugo, Nelly R., Ngure, Kenneth, Benet, Leslie Z., Okochi, Hideaki, Wang, Guohong, Vincent, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428441/
https://www.ncbi.nlm.nih.gov/pubmed/30906930
http://dx.doi.org/10.1016/j.eclinm.2018.08.004