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Development and Validation of an Immunoassay for Tenofovir in Urine as a Real-Time Metric of Antiretroviral Adherence
BACKGROUND: Pharmacologic adherence measures were critical to the interpretation of the tenofovir (TFV)-disoproxil-fumarate/emtricitabine (TDF/FTC) PrEP trials. These measures are being incorporated into PrEP demonstration projects, but currently-available metrics in plasma, cells, hair or urine inv...
Autores principales: | Gandhi, Monica, Bacchetti, Peter, Rodrigues, Warren C., Spinelli, Matthew, Koss, Catherine A., Drain, Paul K., Baeten, Jared M., Mugo, Nelly R., Ngure, Kenneth, Benet, Leslie Z., Okochi, Hideaki, Wang, Guohong, Vincent, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428441/ https://www.ncbi.nlm.nih.gov/pubmed/30906930 http://dx.doi.org/10.1016/j.eclinm.2018.08.004 |
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