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Rhinacanthin-C Extracted from Rhinacanthus nasutus (L.) Inhibits Cholangiocarcinoma Cell Migration and Invasion by Decreasing MMP-2, uPA, FAK and MAPK Pathways

Cholangiocarcinoma is a malignant tumor with high metastatic and mortality rates. We investigated the effects of rhinacanthin-C on cell proliferation, migration, invasion and the expression of proteins regulating cancer cell invasion-regulated proteins in a cholangiocarcinoma (KKU-M156) cell line. C...

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Detalles Bibliográficos
Autores principales: Boueroy, Parichart, Saensa-Ard, Sunitta, Siripong, Pongpun, Kanthawong, Sakawrat, Hahnvajanawong, Chariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428551/
https://www.ncbi.nlm.nih.gov/pubmed/30583689
http://dx.doi.org/10.31557/APJCP.2018.19.12.3605