Cargando…
Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation
The Lin28b(+)Let7(−) axis in fetal/neonatal development plays a role in promoting CD5(+) B1a cell generation as a B-1 B cell developmental outcome. Here we identify the Let7 target, Arid3a, as a crucial molecular effector of the B-1 cell developmental program. Arid3a expression is increased at pro-B...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428705/ https://www.ncbi.nlm.nih.gov/pubmed/30930899 http://dx.doi.org/10.3389/fimmu.2019.00457 |