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Homer1a Attenuates Endoplasmic Reticulum Stress-Induced Mitochondrial Stress After Ischemic Reperfusion Injury by Inhibiting the PERK Pathway

Homer1a is the short form of a scaffold protein that plays a protective role in many forms of stress. However, the role of Homer1a in cerebral ischemia/reperfusion (I/R) injury and its potential mechanism is still unknown. In this study, we found that Homer1a was upregulated by oxygen and glucose de...

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Detalles Bibliográficos
Autores principales: Wei, Jialiang, Wu, Xiuquan, Luo, Peng, Yue, Kangyi, Yu, Yang, Pu, Jingnan, Zhang, Lei, Dai, Shuhui, Han, Donghui, Fei, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428733/
https://www.ncbi.nlm.nih.gov/pubmed/30930751
http://dx.doi.org/10.3389/fncel.2019.00101