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CD117 (c-Kit) Is Expressed During CD8(+) T Cell Priming and Stratifies Sensitivity to Apoptosis According to Strength of TCR Engagement

CD117 (cKit) is the receptor for stem cell factor (SCF) and plays an important role in early haemopoiesis. We show that CD117 is also expressed following priming of mature human CD8(+) T cells in vitro and is detectable following primary infection in vivo. CD117 expression is mediated through an int...

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Detalles Bibliográficos
Autores principales: Frumento, Guido, Zuo, Jianmin, Verma, Kriti, Croft, Wayne, Ramagiri, Pradeep, Chen, Frederick E., Moss, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428734/
https://www.ncbi.nlm.nih.gov/pubmed/30930902
http://dx.doi.org/10.3389/fimmu.2019.00468