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CD117 (c-Kit) Is Expressed During CD8(+) T Cell Priming and Stratifies Sensitivity to Apoptosis According to Strength of TCR Engagement
CD117 (cKit) is the receptor for stem cell factor (SCF) and plays an important role in early haemopoiesis. We show that CD117 is also expressed following priming of mature human CD8(+) T cells in vitro and is detectable following primary infection in vivo. CD117 expression is mediated through an int...
Autores principales: | Frumento, Guido, Zuo, Jianmin, Verma, Kriti, Croft, Wayne, Ramagiri, Pradeep, Chen, Frederick E., Moss, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428734/ https://www.ncbi.nlm.nih.gov/pubmed/30930902 http://dx.doi.org/10.3389/fimmu.2019.00468 |
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