A post-translational modification of human Norovirus capsid protein attenuates glycan binding

Attachment of human noroviruses to histo blood group antigens (HBGAs) is essential for infection, but how this binding event promotes the infection of host cells is unknown. Here, we employ protein NMR experiments supported by mass spectrometry and crystallography to study HBGA binding to the P-doma...

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Detalles Bibliográficos
Autores principales: Mallagaray, Alvaro, Creutznacher, Robert, Dülfer, Jasmin, Mayer, Philipp H. O., Grimm, Lena Lisbeth, Orduña, Jose Maria, Trabjerg, Esben, Stehle, Thilo, Rand, Kasper D., Blaum, Bärbel S., Uetrecht, Charlotte, Peters, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428809/
https://www.ncbi.nlm.nih.gov/pubmed/30899001
http://dx.doi.org/10.1038/s41467-019-09251-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428809/
https://www.ncbi.nlm.nih.gov/pubmed/30899001
http://dx.doi.org/10.1038/s41467-019-09251-5

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