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AKT1(low) quiescent cancer cells in ductal carcinoma in situ of the breast

Ductal carcinoma in situ (DCIS) of the breast precedes the development of invasive breast cancer and reflects the genomic changes and protein expression profile of invasive disease. AKT1(low) cancer cells (QCC) are a rare, drug-tolerant, epigenetically plastic, and quiescent cancer cell subset that...

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Detalles Bibliográficos
Autores principales: Kabraji, Sheheryar, Sole, Xaiver, Huang, Ying, Bango, Clyde, Sgroi, Dennis, Loda, Massimo, Ramaswamy, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428812/
https://www.ncbi.nlm.nih.gov/pubmed/30911675
http://dx.doi.org/10.1038/s41523-019-0105-y