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Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner

Macroautophagy is an evolutionarily conserved cellular maintenance program, meant to protect the brain from premature aging and neurodegeneration. How neuronal autophagy, usually loosing efficacy with age, intersects with neuronal processes mediating brain maintenance remains to be explored. Here, w...

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Detalles Bibliográficos
Autores principales: Bhukel, Anuradha, Beuschel, Christine Brigitte, Maglione, Marta, Lehmann, Martin, Juhász, Gabor, Madeo, Frank, Sigrist, Stephan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428838/
https://www.ncbi.nlm.nih.gov/pubmed/30899013
http://dx.doi.org/10.1038/s41467-019-09262-2