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Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner
Macroautophagy is an evolutionarily conserved cellular maintenance program, meant to protect the brain from premature aging and neurodegeneration. How neuronal autophagy, usually loosing efficacy with age, intersects with neuronal processes mediating brain maintenance remains to be explored. Here, w...
Autores principales: | Bhukel, Anuradha, Beuschel, Christine Brigitte, Maglione, Marta, Lehmann, Martin, Juhász, Gabor, Madeo, Frank, Sigrist, Stephan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428838/ https://www.ncbi.nlm.nih.gov/pubmed/30899013 http://dx.doi.org/10.1038/s41467-019-09262-2 |
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