Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model

The targeting of specific tissue is a major challenge for the effective use of therapeutics and agents mediating this targeting are strongly demanded. We report here on an in vivo selection technology that enables the de novo identification of pegylated DNA aptamers pursuing tissue sites harbouring...

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Detalles Bibliográficos
Autores principales: Civit, Laia, Theodorou, Ioanna, Frey, Franziska, Weber, Holger, Lingnau, Andreas, Gröber, Carsten, Blank, Michael, Dambrune, Chloé, Stunden, James, Beyer, Marc, Schultze, Joachim, Latz, Eicke, Ducongé, Frédéric, Kubbutat, Michael H. G., Mayer, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428855/
https://www.ncbi.nlm.nih.gov/pubmed/30899039
http://dx.doi.org/10.1038/s41598-019-41460-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428855/
https://www.ncbi.nlm.nih.gov/pubmed/30899039
http://dx.doi.org/10.1038/s41598-019-41460-2

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