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Large-scale network analysis reveals the sequence space architecture of antibody repertoires

The architecture of mouse and human antibody repertoires is defined by the sequence similarity networks of the clones that compose them. The major principles that define the architecture of antibody repertoires have remained largely unknown. Here, we establish a high-performance computing platform t...

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Detalles Bibliográficos
Autores principales: Miho, Enkelejda, Roškar, Rok, Greiff, Victor, Reddy, Sai T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428871/
https://www.ncbi.nlm.nih.gov/pubmed/30899025
http://dx.doi.org/10.1038/s41467-019-09278-8