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Large-scale network analysis reveals the sequence space architecture of antibody repertoires
The architecture of mouse and human antibody repertoires is defined by the sequence similarity networks of the clones that compose them. The major principles that define the architecture of antibody repertoires have remained largely unknown. Here, we establish a high-performance computing platform t...
Autores principales: | Miho, Enkelejda, Roškar, Rok, Greiff, Victor, Reddy, Sai T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428871/ https://www.ncbi.nlm.nih.gov/pubmed/30899025 http://dx.doi.org/10.1038/s41467-019-09278-8 |
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