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The RNA Processing Factor Y14 Participates in DNA Damage Response and Repair

DNA repair deficiency leads to genome instability and hence human disease. Depletion of the RNA processing factor Y14/RBM8A in cultured cells or Rbm8a haplodeficiency in the developing mouse cortex results in the accumulation of DNA damage. Y14 depletion differentially affected the expression of DNA...

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Detalles Bibliográficos
Autores principales: Chuang, Tzu-Wei, Lu, Chia-Chen, Su, Chun-Hao, Wu, Pei-Yu, Easwvaran, Sarasvathi, Lee, Chi-Chieh, Kuo, Hung-Che, Hung, Kuan-Yang, Lee, Kuo-Ming, Tsai, Ching-Yen, Tarn, Woan-Yuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428943/
https://www.ncbi.nlm.nih.gov/pubmed/30901577
http://dx.doi.org/10.1016/j.isci.2019.03.005