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Glu-108 in Saccharomyces cerevisiae Rad51 Is Critical for DNA Damage-Induced Nuclear Function

DNA damage-induced Rad51 focus formation is the hallmark of homologous recombination-mediated DNA repair. Earlier, we reported that Rad51 physically interacts with Hsp90, and under the condition of Hsp90 inhibition, it undergoes proteasomal degradation. Here, we show that the dynamic interaction bet...

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Detalles Bibliográficos
Autores principales: Suhane, Tanvi, Bindumadhavan, Vijayalakshmi, Fangaria, Nupur, Nair, Achuthsankar S., Tabassum, Wahida, Muley, Poorvaja, Bhattacharyya, Mrinal K., Bhattacharyya, Sunanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429042/
https://www.ncbi.nlm.nih.gov/pubmed/30894431
http://dx.doi.org/10.1128/mSphere.00082-19