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Evaluation of the Inhibitory Effects of (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one (DiNap), a Natural Product Analog, on the Replication of Type 2 PRRSV In Vitro and In Vivo

DiNap [(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one], an analog of a natural product (the chalcone flavokawain), was synthesized and characterized in this study. Porcine reproductive and respiratory syndrome virus (PRRSV) is the most challenging threat to the swine indust...

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Detalles Bibliográficos
Autores principales: Khatun, Amina, Park, Sun You, Shabir, Nadeem, Nazki, Salik, Kang, A-Rum, Jeong, Chang-Gi, Seo, Byoung-Joo, Yang, Myeon-Sik, Kim, Bumseok, Seo, Young Ho, Kim, Won-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429065/
https://www.ncbi.nlm.nih.gov/pubmed/30832429
http://dx.doi.org/10.3390/molecules24050887