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HER2 Directed Antibody-Drug-Conjugates beyond T-DM1 in Breast Cancer

Since the discovery of the human epidermal growth factor receptor 2 (HER2) as an oncogenic driver in a subset of breast cancers and the development of HER2 directed therapies, the prognosis of HER2 amplified breast cancers has improved meaningfully. Next to monoclonal anti-HER2 antibodies and tyrosi...

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Detalles Bibliográficos
Autores principales: Rinnerthaler, Gabriel, Gampenrieder, Simon Peter, Greil, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429068/
https://www.ncbi.nlm.nih.gov/pubmed/30841523
http://dx.doi.org/10.3390/ijms20051115