Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway

Transcription factors play a significant role during the symptomatic onset and progression of prion diseases. We previously showed the immunomodulatory and nuclear factor of activated T cells’ (NFAT) suppressive effects of an immunosuppressant, FK506, in the symptomatic stage and an antibiotic, mino...

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Detalles Bibliográficos
Autores principales: Shah, Syed Zahid Ali, Zhao, Deming, Taglialatela, Giulio, Hussain, Tariq, Dong, Haodi, Sabir, Naveed, Mangi, Mazhar Hussain, Wu, Wei, Lai, Mengyu, Zhang, Xixi, Duan, Yuhan, Wang, Lu, Zhou, Xiangmei, Yang, Lifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429086/
https://www.ncbi.nlm.nih.gov/pubmed/30845718
http://dx.doi.org/10.3390/ijms20051144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429086/
https://www.ncbi.nlm.nih.gov/pubmed/30845718
http://dx.doi.org/10.3390/ijms20051144

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