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Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway
Transcription factors play a significant role during the symptomatic onset and progression of prion diseases. We previously showed the immunomodulatory and nuclear factor of activated T cells’ (NFAT) suppressive effects of an immunosuppressant, FK506, in the symptomatic stage and an antibiotic, mino...
Autores principales: | Shah, Syed Zahid Ali, Zhao, Deming, Taglialatela, Giulio, Hussain, Tariq, Dong, Haodi, Sabir, Naveed, Mangi, Mazhar Hussain, Wu, Wei, Lai, Mengyu, Zhang, Xixi, Duan, Yuhan, Wang, Lu, Zhou, Xiangmei, Yang, Lifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429086/ https://www.ncbi.nlm.nih.gov/pubmed/30845718 http://dx.doi.org/10.3390/ijms20051144 |
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