Thymoquinone Selectively Kills Hypoxic Renal Cancer Cells by Suppressing HIF-1α-Mediated Glycolysis

Several reports have shown that thymoquinone (TQ) effectively attenuates angiogenesis in cancer cells, resulting in suppression of tumor growth. However, it is not yet clear whether TQ reduces hypoxia-inducible factor-1α (HIF-1α) expression in hypoxic cancer cells. Here, we found that TQ was a novel...

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Detalles Bibliográficos
Autores principales: Lee, Yoon-Mi, Kim, Geon-Hee, Park, Eun-Ji, Oh, Taek-In, Lee, Sujin, Kan, Sang-Yeon, Kang, Hyeji, Kim, Byeong Mo, Kim, Ji Hyung, Lim, Ji-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429094/
https://www.ncbi.nlm.nih.gov/pubmed/30832444
http://dx.doi.org/10.3390/ijms20051092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429094/
https://www.ncbi.nlm.nih.gov/pubmed/30832444
http://dx.doi.org/10.3390/ijms20051092

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