Multi-Steps Fragmentation-Ion Trap Mass Spectrometry Coupled to Liquid Chromatography Diode Array System for Investigation of Olaparib Related Substances

A high-performance liquid chromatography-diode array-mass spectrometric (LC-DAD-MS) method was developed and validated to investigate the related substances of olaparib (OLA) in bulk form. OLA was exposed to acid–base hydrolysis, boiling, oxidation with hydrogen peroxide, and UV light followed by LC...

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Detalles Bibliográficos
Autores principales: Khedr, Alaa, El-Hay, Soad S. Abd, Kammoun, Ahmed K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429096/
https://www.ncbi.nlm.nih.gov/pubmed/30818845
http://dx.doi.org/10.3390/molecules24050843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429096/
https://www.ncbi.nlm.nih.gov/pubmed/30818845
http://dx.doi.org/10.3390/molecules24050843

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