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Abdominal Fat SIRT6 Expression and Its Relationship with Inflammatory and Metabolic Pathways in Pre-Diabetic Overweight Patients

The role of sirtuin 6 (SIRT6) in adipose abdominal tissue of pre-diabetic (pre-DM) patients is poorly known. Here, we evaluated SIRT6 expression in visceral abdominal fat of obese pre-diabetic patients and the potential effects of metformin therapy. Results indicated that obese pre-DM subjects showe...

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Detalles Bibliográficos
Autores principales: D’Onofrio, Nunzia, Pieretti, Gorizio, Ciccarelli, Feliciano, Gambardella, Antonio, Passariello, Nicola, Rizzo, Maria Rosaria, Barbieri, Michelangela, Marfella, Raffaele, Nicoletti, Gianfranco, Balestrieri, Maria Luisa, Sardu, Celestino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429119/
https://www.ncbi.nlm.nih.gov/pubmed/30845774
http://dx.doi.org/10.3390/ijms20051153