Cargando…

Abdominal Fat SIRT6 Expression and Its Relationship with Inflammatory and Metabolic Pathways in Pre-Diabetic Overweight Patients

The role of sirtuin 6 (SIRT6) in adipose abdominal tissue of pre-diabetic (pre-DM) patients is poorly known. Here, we evaluated SIRT6 expression in visceral abdominal fat of obese pre-diabetic patients and the potential effects of metformin therapy. Results indicated that obese pre-DM subjects showe...

Descripción completa

Detalles Bibliográficos
Autores principales:	D’Onofrio, Nunzia, Pieretti, Gorizio, Ciccarelli, Feliciano, Gambardella, Antonio, Passariello, Nicola, Rizzo, Maria Rosaria, Barbieri, Michelangela, Marfella, Raffaele, Nicoletti, Gianfranco, Balestrieri, Maria Luisa, Sardu, Celestino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429119/ https://www.ncbi.nlm.nih.gov/pubmed/30845774 http://dx.doi.org/10.3390/ijms20051153

Ejemplares similares

Inflammatory Cytokines and SIRT1 Levels in Subcutaneous Abdominal Fat: Relationship With Cardiac Performance in Overweight Pre-diabetics Patients
por: Sardu, Celestino, et al.
Publicado: (2018)

Effects of incretin treatment on cardiovascular outcomes in diabetic STEMI-patients with culprit obstructive and multivessel non obstructive-coronary-stenosis
por: Marfella, Raffaele, et al.
Publicado: (2018)

Hyperglycaemia on admission to hospital and COVID-19
por: Sardu, Celestino, et al.
Publicado: (2020)

Outcomes in Patients With Hyperglycemia Affected by COVID-19: Can We Do More on Glycemic Control?
por: Sardu, Celestino, et al.
Publicado: (2020)

MiR-15b-5p and PCSK9 inhibition reduces lipopolysaccharide-induced endothelial dysfunction by targeting SIRT4
por: Martino, Elisa, et al.
Publicado: (2023)

Cardiac Resynchronization Therapy Outcomes in Type 2 Diabetic Patients: Role of MicroRNA Changes
por: Sardu, Celestino, et al.
Publicado: (2016)

SIRT3 mediates the effects of PCSK9 inhibitors on inflammation, autophagy, and oxidative stress in endothelial cells
por: D'Onofrio, Nunzia, et al.
Publicado: (2023)

Pericoronary fat inflammation and Major Adverse Cardiac Events (MACE) in prediabetic patients with acute myocardial infarction: effects of metformin
por: Sardu, Celestino, et al.
Publicado: (2019)

Milk Exosomal miR-27b Worsen Endoplasmic Reticulum Stress Mediated Colorectal Cancer Cell Death
por: Martino, Elisa, et al.
Publicado: (2022)

Adiponectin Related Vascular and Cardiac Benefits in Obesity: Is There a Role for an Epigenetically Regulated Mechanism?
por: Fontanella, Rosaria Anna, et al.
Publicado: (2021)

Awaking Blood Pressure Surge and Progression to Microalbuminuria in Type 2 Normotensive Diabetic Patients
por: Barbieri, Michelangela, et al.
Publicado: (2016)

ELectrophysiological mechanisms underlying the Inhibitory CArdiac syncope without asystolic significant pause: Therapeutic and prognostic implications. The ELICA randomized trial
por: Sardu, Celestino, et al.
Publicado: (2018)

Cardiac electrophysiological alterations and clinical response in cardiac resynchronization therapy with a defibrillator treated patients affected by metabolic syndrome
por: Sardu, Celestino, et al.
Publicado: (2017)

Serum adiponectin levels are associated with worse cognitive function in postmenopausal women
por: De Franciscis, Pasquale, et al.
Publicado: (2017)

Multipolar pacing by cardiac resynchronization therapy with a defibrillators treatment in type 2 diabetes mellitus failing heart patients: impact on responders rate, and clinical outcomes
por: Sardu, Celestino, et al.
Publicado: (2017)

Sodium-glucose co-transporter2 expression and inflammatory activity in diabetic atherosclerotic plaques: Effects of sodium-glucose co-transporter2 inhibitor treatment
por: D'Onofrio, Nunzia, et al.
Publicado: (2021)

Reduction of Oxidative Stress and Inflammation by Blunting Daily Acute Glucose Fluctuations in Patients With Type 2 Diabetes: Role of dipeptidyl peptidase-IV inhibition
por: Rizzo, Maria Rosaria, et al.
Publicado: (2012)

Response to Comment on: Rizzo et al. Reduction of Oxidative Stress and Inflammation by Blunting Daily Acute Glucose Fluctuations in Patients With Type 2 Diabetes: Role of Dipeptidyl Peptidase-IV Inhibition. Diabetes Care 2012;35:2076–2082
por: Rizzo, Maria Rosaria, et al.
Publicado: (2013)

Cardiac resynchronization therapy with a defibrillator (CRTd) in failing heart patients with type 2 diabetes mellitus and treated by glucagon-like peptide 1 receptor agonists (GLP-1 RA) therapy vs. conventional hypoglycemic drugs: arrhythmic burden, hospitalizations for heart failure, and CRTd responders rate
por: Sardu, Celestino, et al.
Publicado: (2018)

Stretch, Injury and Inflammation Markers Evaluation to Predict Clinical Outcomes After Implantable Cardioverter Defibrillator Therapy in Heart Failure Patients With Metabolic Syndrome
por: Sardu, Celestino, et al.
Publicado: (2018)

Metabolic syndrome is associated with a poor outcome in patients affected by outflow tract premature ventricular contractions treated by catheter ablation
por: Sardu, Celestino, et al.
Publicado: (2014)

Glycaemic control is associated with SARS-CoV-2 breakthrough infections in vaccinated patients with type 2 diabetes
por: Marfella, Raffaele, et al.
Publicado: (2022)

SARS-COV-2 colonizes coronary thrombus and impairs heart microcirculation bed in asymptomatic SARS-CoV-2 positive subjects with acute myocardial infarction
por: Marfella, Raffaele, et al.
Publicado: (2021)

Metformin Therapy Effects on the Expression of Sodium-Glucose Cotransporter 2, Leptin, and SIRT6 Levels in Pericoronary Fat Excised from Pre-Diabetic Patients with Acute Myocardial Infarction
por: Sardu, Celestino, et al.
Publicado: (2021)

Correction to: Thrombus aspiration in hyperglycemic ST-elevation myocardial infarction (STEMI) patients: clinical outcomes at 1-year follow-up
por: Sardu, Celestino, et al.
Publicado: (2018)

Thrombus aspiration in hyperglycemic ST-elevation myocardial infarction (STEMI) patients: clinical outcomes at 1-year follow-up
por: Sardu, Celestino, et al.
Publicado: (2018)

Association of Genetic Variation in Adaptor Protein APPL1/APPL2 Loci with Non-Alcoholic Fatty Liver Disease
por: Barbieri, Michelangela, et al.
Publicado: (2013)

Mediterranean Diet, Telomere Maintenance and Health Status among Elderly
por: Boccardi, Virginia, et al.
Publicado: (2013)

Glycated ACE2 receptor in diabetes: open door for SARS-COV-2 entry in cardiomyocyte
por: D’Onofrio, Nunzia, et al.
Publicado: (2021)

Autonomic Nervous System and Cognitive Impairment in Older Patients: Evidence From Long-Term Heart Rate Variability in Real-Life Setting
por: Dalise, Anna Maria, et al.
Publicado: (2020)

SIRT3 and Metabolic Reprogramming Mediate the Antiproliferative Effects of Whey in Human Colon Cancer Cells
por: D’Onofrio, Nunzia, et al.
Publicado: (2021)

Does poor glycaemic control affect the immunogenicity of the COVID‐19 vaccination in patients with type 2 diabetes: The CAVEAT study
por: Marfella, Raffaele, et al.
Publicado: (2021)

Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? A Comprehensive Evaluation of Clinical and Basic Evidence
por: Sardu, Celestino, et al.
Publicado: (2020)

Relationships Between Daily Acute Glucose Fluctuations and Cognitive Performance Among Aged Type 2 Diabetic Patients
por: Rizzo, Maria Rosaria, et al.
Publicado: (2010)

SIRT3 Modulates Endothelial Mitochondrial Redox State during Insulin Resistance
por: Martino, Elisa, et al.
Publicado: (2022)

Phenolic Profiles of Red Wine Relate to Vascular Endothelial Benefits Mediated by SIRT1 and SIRT6
por: D’Onofrio, Nunzia, et al.
Publicado: (2021)

Bariatric Surgery Reduces Oxidative Stress by Blunting 24-h Acute Glucose Fluctuations in Type 2 Diabetic Obese Patients
por: Marfella, Raffaele, et al.
Publicado: (2010)

Atherosclerotic Plaque Fissuration and Clinical Outcomes in Pre-Diabetics vs. Normoglycemics Patients Affected by Asymptomatic Significant Carotid Artery Stenosis at 2 Years of Follow-Up: Role of microRNAs Modulation: The ATIMIR Study
por: Sardu, Celestino, et al.
Publicado: (2021)

miR-21 in Human Cardiomyopathies
por: Surina,, et al.
Publicado: (2021)

Corrigendum: miR-21 in Human Cardiomyopathies
por: Surina,, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0eseebs6gcnbv56hpafq7no937