Identification of Compounds That Inhibit Estrogen-Related Receptor Alpha Signaling Using High-Throughput Screening Assays

The nuclear receptor, estrogen-related receptor alpha (ERRα; NR3B1), plays a pivotal role in energy homeostasis. Its expression fluctuates with the demands of energy production in various tissues. When paired with the peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), the PGC/ERR...

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Detalles Bibliográficos
Autores principales: Lynch, Caitlin, Zhao, Jinghua, Sakamuru, Srilatha, Zhang, Li, Huang, Ruili, Witt, Kristine L., Merrick, B. Alex, Teng, Christina T., Xia, Menghang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429183/
https://www.ncbi.nlm.nih.gov/pubmed/30818834
http://dx.doi.org/10.3390/molecules24050841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429183/
https://www.ncbi.nlm.nih.gov/pubmed/30818834
http://dx.doi.org/10.3390/molecules24050841

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