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One-Pot NBS-Promoted Synthesis of Imidazoles and Thiazoles from Ethylarenes in Water
A facile and eco-friendly method has been developed for the synthesis of imidazoles and thiazoles from ethylarenes in water. The reaction proceeds via in situ formation of α-bromoketone using NBS as a bromine source as well as an oxidant, followed by trapping with suitable nucleophiles to provide th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429224/ https://www.ncbi.nlm.nih.gov/pubmed/30836604 http://dx.doi.org/10.3390/molecules24050893 |