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Design and Synthesis of Novel Anti-Proliferative Emodin Derivatives and Studies on their Cell Cycle Arrest, Apoptosis Pathway and Migration

Emodin is a cell arrest and apoptosis-inducing compound that is widely distributed in different plants (rhubarb, aloe), lichens and terrestrial fungi, and also isolated from marine-derived fungi and marine sponge-associated fungi. In this study, we designed and synthesized a novel series of emodin d...

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Detalles Bibliográficos
Autores principales: Yang, Kun, Jin, Ming-Ji, Quan, Zhe-Shan, Piao, Hu-Ri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429262/
https://www.ncbi.nlm.nih.gov/pubmed/30832378
http://dx.doi.org/10.3390/molecules24050884