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Evolution and Antibacterial Evaluation of 8-Hydroxy-cycloberberine Derivatives as a Novel Family of Antibacterial Agents Against MRSA

Twenty-five new derivatives of 8-hydroxycycloberberine (1) were synthesized and evaluated for their activities against Gram-positive bacteria, taking 1 as the lead. Part of them displayed satisfactory antibacterial activities against methicillin-susceptible Staphylococcus aureus (MSSA) and methicill...

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Detalles Bibliográficos
Autores principales: Yang, Yuan-Shuai, Wei, Wei, Hu, Xin-Xin, Tang, Sheng, Pang, Jing, You, Xue-Fu, Fan, Tian-Yun, Wang, Yan-Xiang, Song, Dan-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429263/
https://www.ncbi.nlm.nih.gov/pubmed/30862066
http://dx.doi.org/10.3390/molecules24050984