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Role of Norepinephrine in IL-1β-Induced Chondrocyte Dedifferentiation under Physioxia

As part of the pathogenesis of osteoarthritis (OA), chondrocytes lose their phenotype and become hypertrophic, or dedifferentiate, mainly driven by interleukin-1β (IL-1β). The contribution of other factors to the dedifferentiation process is not completely understood. Recent studies suggested a dose...

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Detalles Bibliográficos
Autores principales: Speichert, Saskia, Molotkov, Natalie, El Bagdadi, Karima, Meurer, Andrea, Zaucke, Frank, Jenei-Lanzl, Zsuzsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429278/
https://www.ncbi.nlm.nih.gov/pubmed/30861996
http://dx.doi.org/10.3390/ijms20051212