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Epigenetic Suppression of the T-box Subfamily 2 (TBX2) in Human Non-Small Cell Lung Cancer

(1) The TBX2 subfamily of transcription factors (TBXs 2, 3, 4 and 5) are markedly down-regulated in human non-small cell lung cancer (NSCLC) and exert tumor suppressor effects in lung malignancy. Yet, mechanisms underlying suppressed expression of the TBX2 subfamily in NSCLC are elusive. Here, we in...

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Detalles Bibliográficos
Autores principales: Nehme, Eliana, Rahal, Zahraa, Sinjab, Ansam, Khalil, Athar, Chami, Hassan, Nemer, Georges, Kadara, Humam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429281/
https://www.ncbi.nlm.nih.gov/pubmed/30866410
http://dx.doi.org/10.3390/ijms20051159