Bee Venom and Its Peptide Component Melittin Suppress Growth and Migration of Melanoma Cells via Inhibition of PI3K/AKT/mTOR and MAPK Pathways

Malignant melanoma is the deadliest form of skin cancer and highly chemoresistant. Melittin, an amphiphilic peptide containing 26 amino acid residues, is the major active ingredient from bee venom (BV). Although melittin is known to have several biological activities such as anti-inflammatory, antib...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Haet Nim, Baek, Seung Bae, Jung, Hye Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429308/
https://www.ncbi.nlm.nih.gov/pubmed/30866426
http://dx.doi.org/10.3390/molecules24050929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429308/
https://www.ncbi.nlm.nih.gov/pubmed/30866426
http://dx.doi.org/10.3390/molecules24050929

Ejemplares similares