Cargando…
Bee Venom and Its Peptide Component Melittin Suppress Growth and Migration of Melanoma Cells via Inhibition of PI3K/AKT/mTOR and MAPK Pathways
Malignant melanoma is the deadliest form of skin cancer and highly chemoresistant. Melittin, an amphiphilic peptide containing 26 amino acid residues, is the major active ingredient from bee venom (BV). Although melittin is known to have several biological activities such as anti-inflammatory, antib...
Autores principales: | Lim, Haet Nim, Baek, Seung Bae, Jung, Hye Jin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429308/ https://www.ncbi.nlm.nih.gov/pubmed/30866426 http://dx.doi.org/10.3390/molecules24050929 |
Ejemplares similares
-
Bee Venom and Its Major Component Melittin Attenuated Cutibacterium acnes- and IGF-1-Induced Acne Vulgaris via Inactivation of Akt/mTOR/SREBP Signaling Pathway
por: Gu, Hyemin, et al.
Publicado: (2022) -
Therapeutic effects of bee venom and its major component, melittin, on atopic dermatitis in vivo and in vitro
por: An, Hyun‐Jin, et al.
Publicado: (2018) -
Anti-Inflammatory Applications of Melittin, a Major Component of Bee Venom: Detailed Mechanism of Action and Adverse Effects
por: Lee, Gihyun, et al.
Publicado: (2016) -
Comparative Study of Antimicrobial Properties of Bee Venom Extracts and Melittins of Honey Bees
por: Maitip, Jakkrawut, et al.
Publicado: (2021) -
Antimicrobial Activity of Bee Venom and Melittin against Borrelia burgdorferi
por: Socarras, Kayla M., et al.
Publicado: (2017)