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CUBAN, a Case Study of Selective Binding: Structural Details of the Discrimination between Ubiquitin and NEDD8

The newly identified CUBAN (Cullin binding domain associating with NEDD8) domain recognizes both ubiquitin and the ubiquitin-like NEDD8. Despite the high similarity between the two molecules, CUBAN shows a clear preference for NEDD8, free and conjugated to cullins. We previously characterized the do...

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Detalles Bibliográficos
Autores principales: Santonico, Elena, Nepravishta, Ridvan, Mandaliti, Walter, Castagnoli, Luisa, Cesareni, Gianni, Paci, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429362/
https://www.ncbi.nlm.nih.gov/pubmed/30857167
http://dx.doi.org/10.3390/ijms20051185