Synthesis of New Indanyl Nucleoside Analogues and their Biological Evaluation on Hepatitis C Virus (HCV) Replicon

Here, we report a convenient synthetic procedure for the preparation of four novel indanyl carbanucleoside derivatives in the racemic form. The action of these compounds against hepatitis C virus was evaluated in vitro using the replicon cell line, Huh7.5 SG. Contrary to our expectations, all these...

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Detalles Bibliográficos
Autores principales: Gómez, Matías E., Gentile, Emiliano A., Martini, M. Florencia, Cuestas, María L., Mathet, Verónica L., Moltrasio, Graciela Y., Moglioni, Albertina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429379/
https://www.ncbi.nlm.nih.gov/pubmed/30862130
http://dx.doi.org/10.3390/molecules24050990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429379/
https://www.ncbi.nlm.nih.gov/pubmed/30862130
http://dx.doi.org/10.3390/molecules24050990

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