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Closure of the Human TKFC Active Site: Comparison of the Apoenzyme and the Complexes Formed with Either Triokinase or FMN Cyclase Substrates

Human triokinase/flavin mononucleotide (FMN) cyclase (hTKFC) catalyzes the adenosine triphosphate (ATP)-dependent phosphorylation of D-glyceraldehyde and dihydroxyacetone (DHA), and the cyclizing splitting of flavin adenine dinucleotide (FAD). hTKFC structural models are dimers of identical subunits...

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Detalles Bibliográficos
Autores principales: Rodrigues, Joaquim Rui, Cameselle, José Carlos, Cabezas, Alicia, Ribeiro, João Meireles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429413/
https://www.ncbi.nlm.nih.gov/pubmed/30836629
http://dx.doi.org/10.3390/ijms20051099