Cargando…
Closure of the Human TKFC Active Site: Comparison of the Apoenzyme and the Complexes Formed with Either Triokinase or FMN Cyclase Substrates
Human triokinase/flavin mononucleotide (FMN) cyclase (hTKFC) catalyzes the adenosine triphosphate (ATP)-dependent phosphorylation of D-glyceraldehyde and dihydroxyacetone (DHA), and the cyclizing splitting of flavin adenine dinucleotide (FAD). hTKFC structural models are dimers of identical subunits...
Autores principales: | Rodrigues, Joaquim Rui, Cameselle, José Carlos, Cabezas, Alicia, Ribeiro, João Meireles |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429413/ https://www.ncbi.nlm.nih.gov/pubmed/30836629 http://dx.doi.org/10.3390/ijms20051099 |
Ejemplares similares
-
Substrate Specificity of Chimeric Enzymes Formed by Interchange of the Catalytic and Specificity Domains of the 5′-Nucleotidase UshA and the 3′-Nucleotidase CpdB
por: Cabezas, Alicia, et al.
Publicado: (2021) -
Molecular Dynamics Approach in the Comparison of Wild-Type and Mutant Paraoxonase-1 Apoenzyme Form
por: Amine, Khadija, et al.
Publicado: (2015) -
Molecular Dissection of Escherichia coli CpdB: Roles of the N Domain in Catalysis and Phosphate Inhibition, and of the C Domain in Substrate Specificity and Adenosine Inhibition
por: López-Villamizar, Iralis, et al.
Publicado: (2021) -
Crystal structures of FMN‐bound and FMN‐free forms of dihydroorotate dehydrogenase from Trypanosoma brucei
por: Kubota, Tomomi, et al.
Publicado: (2018) -
Characterization of Danio rerio Mn(2+)-Dependent ADP-Ribose/CDP-Alcohol Diphosphatase, the Structural Prototype of the ADPRibase-Mn-Like Protein Family
por: Rodrigues, Joaquim Rui, et al.
Publicado: (2012)