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Investigation of 8-Aza-7-Deaza Purine Nucleoside Derivatives

Glycosylation of 6-amino-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine and its iodo- and bromo- analogues with the protected ribofuranose and 2′-deoxyribofuranose under different conditions resulted in the synthesis of N(9)- and N(8)-glycosylated purine nucleosides. Five key intermediate nucleosides, havin...

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Detalles Bibliográficos
Autores principales: Ren, Hang, An, Haoyun, Tao, Jingchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429420/
https://www.ncbi.nlm.nih.gov/pubmed/30862058
http://dx.doi.org/10.3390/molecules24050983