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Immobilization of Denosumab on Titanium Affects Osteoclastogenesis of Human Peripheral Blood Monocytes

Immobilization of proteins has been examined to improve implant surfaces. In this study, titanium surfaces were modified with nanofunctionalized denosumab (cDMAB), a human monoclonal anti-RANKL IgG. Noncoding DNA oligonucleotides (ODN) served as linker molecules between titanium and DMAB. Binding an...

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Detalles Bibliográficos
Autores principales: Beck, Felicitas, Hartmann, Eliza S., Koehler, Miriam I., Redeker, Julia I., Schluessel, Sabine, Schmitt, Baerbel, Fottner, Andreas, Unger, Marina, van Griensven, Martijn, Michael, Jan, Summer, Burkhard, Kunzelmann, Karl-Heinz, Beutner, Rene, Scharnweber, Dieter, Kostenuik, Paul J., Mayer-Wagner, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429431/
https://www.ncbi.nlm.nih.gov/pubmed/30813507
http://dx.doi.org/10.3390/ijms20051002