Phenethyl Isothiocyanate Exposure Promotes Oxidative Stress and Suppresses Sp1 Transcription Factor in Cancer Stem Cells

Aldehyde dehydrogenase 1 (ALDH1) is a cytosolic marker of cancer stem cells (CSCs), which are a sub-population within heterogeneous tumor cells. CSCs associate with therapy-resistance, self-renewal, malignancy, tumor-relapse, and reduced patient-survival window. ALDH1-mediated aldehyde scavenging he...

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Detalles Bibliográficos
Autores principales: Upadhyaya, Bijaya, Liu, Yi, Dey, Moul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429440/
https://www.ncbi.nlm.nih.gov/pubmed/30818757
http://dx.doi.org/10.3390/ijms20051027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429440/
https://www.ncbi.nlm.nih.gov/pubmed/30818757
http://dx.doi.org/10.3390/ijms20051027

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