Sirtuins in Alzheimer’s Disease: SIRT2-Related GenoPhenotypes and Implications for PharmacoEpiGenetics

Sirtuins (SIRT1-7) are NAD(+)-dependent protein deacetylases/ADP ribosyltransferases with important roles in chromatin silencing, cell cycle regulation, cellular differentiation, cellular stress response, metabolism and aging. Sirtuins are components of the epigenetic machinery, which is disturbed i...

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Detalles Bibliográficos
Autores principales: Cacabelos, Ramón, Carril, Juan C., Cacabelos, Natalia, Kazantsev, Aleksey G., Vostrov, Alex V., Corzo, Lola, Cacabelos, Pablo, Goldgaber, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429449/
https://www.ncbi.nlm.nih.gov/pubmed/30871086
http://dx.doi.org/10.3390/ijms20051249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429449/
https://www.ncbi.nlm.nih.gov/pubmed/30871086
http://dx.doi.org/10.3390/ijms20051249

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