Sirtuins in Alzheimer’s Disease: SIRT2-Related GenoPhenotypes and Implications for PharmacoEpiGenetics

Sirtuins (SIRT1-7) are NAD(+)-dependent protein deacetylases/ADP ribosyltransferases with important roles in chromatin silencing, cell cycle regulation, cellular differentiation, cellular stress response, metabolism and aging. Sirtuins are components of the epigenetic machinery, which is disturbed i...

Descripción completa

Detalles Bibliográficos
Autores principales: Cacabelos, Ramón, Carril, Juan C., Cacabelos, Natalia, Kazantsev, Aleksey G., Vostrov, Alex V., Corzo, Lola, Cacabelos, Pablo, Goldgaber, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429449/
https://www.ncbi.nlm.nih.gov/pubmed/30871086
http://dx.doi.org/10.3390/ijms20051249

Ejemplares similares

Ejemplares similares