Low-Frequency Mutational Heterogeneity of Invasive Ductal Carcinoma Subtypes: Information to Direct Precision Oncology

Information regarding the role of low-frequency hotspot cancer-driver mutations (CDMs) in breast carcinogenesis and therapeutic response is limited. Using the sensitive and quantitative Allele-specific Competitor Blocker PCR (ACB-PCR) approach, mutant fractions (MFs) of six CDMs (PIK3CA H1047R and E...

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Detalles Bibliográficos
Autores principales: Myers, Meagan B., McKim, Karen L., Banda, Malathi, George, Nysia I., Parsons, Barbara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429455/
https://www.ncbi.nlm.nih.gov/pubmed/30813596
http://dx.doi.org/10.3390/ijms20051011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429455/
https://www.ncbi.nlm.nih.gov/pubmed/30813596
http://dx.doi.org/10.3390/ijms20051011

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