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Green Methodologies for Copper(I)-Catalyzed Azide-Alkyne Cycloadditions: A Comparative Study

Successful copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions may be achieved by several methods. In this paper, four synthetic protocols were performed for direct comparison of time required for the synthesis, yield, and purity of the 1H-1,2,3-triazole products. The methods with Cu(I)...

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Detalles Bibliográficos
Autores principales: Trujillo, Marissa, Hull-Crew, Clayton, Outlaw, Andrew, Stewart, Kevin, Taylor, Loren, George, Laura, Duensing, Allison, Tracey, Breanna, Schoffstall, Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429464/
https://www.ncbi.nlm.nih.gov/pubmed/30857343
http://dx.doi.org/10.3390/molecules24050973