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Primary α-tertiary amine synthesis via α-C–H functionalization

A quinone-mediated general synthetic platform for the construction of primary α-tertiary amines from abundant primary α-branched amine starting materials is described. This procedure pivots on the efficient in situ generation of reactive ketimine intermediates and subsequent reaction with carbon-cen...

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Detalles Bibliográficos
Autores principales: Vasu, Dhananjayan, Fuentes de Arriba, Angel L., Leitch, Jamie A., de Gombert, Antoine, Dixon, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429468/
https://www.ncbi.nlm.nih.gov/pubmed/30996928
http://dx.doi.org/10.1039/c8sc05164j